OUR PLATFORM
Three layers. One scientific platform.
Hordago separates product shells, scientific engines, and execution infrastructure. This allows new domain products to be generated without rebuilding the stack from scratch.
Platform Architecture
Built in Layers
Domain Operating Systems
Shared Scientific Engines
Factory & Execution
LAYER 1
Domain Operating Systems
Purpose-built operating systems for specific scientific domains. Thin shells powered by shared engines.
CRISPRos
CRISPR Experiment Operating System
End-to-end CRISPR perturbation workflows with human approval at every decision gate. Full provenance on every experiment.
GWASos
GWAS Analysis Operating System
AI-assisted rare variant prioritization with human-verified regulatory effect predictions. Calibrated uncertainty for confident target selection.
LAYER 2
Shared Scientific Engines
The reusable substrate that powers every DomainOS product.
biocontext7
Tool Discovery Intelligence
47,000+ bioinformatics tools scored and indexed.
paper-intelligence
Literature Analysis Engine
Structured citation graphs and literature triage.
co-scientist
Scientific Reasoning Engine
Hypothesis generation with mandatory falsification plans. Evidence-locked reasoning, not hallucination.
co-writer
Manuscript Drafting Engine
Grounded manuscript drafting from artifacts.
Knowledge Graph
Scientific Knowledge Graph
Connected knowledge across papers, experiments, and datasets.
LAYER 3
Factory & Execution
How Hordago manufactures scientific products.
Scientific Compiler
Deterministic Build System
Spec Engine
Work Decomposition
Agentic Orchestration
Parallel Execution
THE FLYWHEEL
How DomainOS products learn
Every experiment makes the system smarter.
Prioritize
Foundation models score rare variants and predict regulatory effects with calibrated uncertainty
Plan
Agentic workflows generate optimized CRISPR perturbation strategies and protocols
Execute
Experiments run with full provenance capture, tracking every parameter and condition
Learn
Outcomes feed back to improve predictions, closing the loop for continuous improvement
Ready to accelerate your research?
Learn how our platform can transform your scientific workflows.