ALL IN ON AI FOR BIOLOGY
Every claim traceable. Every figure reproducible. Every experiment auditable.
Evidence-first AI infrastructure for life sciences. Scientists stay in command.
THE APPROACH
The compiler for biology.
Most AI tools generate plausible-sounding science with no audit trail. Hordago compiles reproducible artifacts from your data and specs — figures, statistics, provenance manifests — without LLM involvement in the deterministic core.
INPUT
Data + Specs
CSV · FASTQ · YAML
COMPILE
Deterministic Pipeline
No LLM in the loop
OUTPUT
Reproducible Artifacts
Figures · Stats · Manifest
BUILT FOR TRUST
Human governance by default.
Agentic AI is powerful — but science demands accountability. Every Hordago product enforces human oversight at decision points.
Human Approval Gates
AI proposes, scientists decide. Every critical action — guide selection, protocol changes, result interpretation — requires explicit human approval.
Full Provenance
Every output includes a manifest: inputs, git commits, tool versions, environment, SHA-256 hashes. Reproduce any result from the manifest alone.
Grounded Claims
Every sentence references a concrete artifact — a figure panel, a statistic, a citation. No hallucinated claims. No unverifiable assertions.
DOMAIN OPERATING SYSTEMS
Hordago. All in on evidence-first science.
Purpose-built operating systems for scientific domains. Thin shells powered by shared scientific engines.
CRISPRos
CRISPR Experiment Operating System
End-to-end CRISPR perturbation workflows with human approval at every decision gate. Full provenance on every experiment.
GWASos
GWAS Analysis Operating System
AI-assisted rare variant prioritization with human-verified regulatory effect predictions. Calibrated uncertainty for confident target selection.
POWERED BY
Shared scientific engines
DomainOS products are thin shells built on reusable scientific engines.
paper-intelligence
Literature Analysis Engine
Structured citation graphs and literature triage.
co-scientist
Scientific Reasoning Engine
Hypothesis generation with mandatory falsification plans. Evidence-locked reasoning, not hallucination.
co-writer
Manuscript Drafting Engine
Grounded manuscript drafting from artifacts.
Knowledge Graph
Scientific Knowledge Graph
Connected knowledge across papers, experiments, and datasets.
THE ARCHITECTURE
Three layers. One platform.
Hordago separates product shells, scientific engines, and execution infrastructure. New domain products ship without rebuilding the stack.
Platform Architecture
Built in Layers
Domain Operating Systems
Shared Scientific Engines
Factory & Execution
INFRASTRUCTURE
How we build scientific products
Scientific Compiler
Deterministic Build System
Spec Engine
Work Decomposition
Agentic Orchestration
Parallel Execution
—
GitHub Stars
4,800+
Executable Scripts
1,100+
Tests
346+
Skills across 32 Plugins
44+
Formal Agents
Stats updated quarterly · Last updated Q1 2026
Integrated with the tools you use
Ready to make your science reproducible?
We're working with early partners in CRISPR and rare disease research.
Get in Touch